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Cell Culture (Media, Sera, Reagents) Markets, 2022 - Biopharmaceuticals Primary Driver of the Cell Culture Market

/EIN News/ -- Dublin, Jan. 14, 2019 (GLOBE NEWSWIRE) -- The "Global Cell Culture Markets (Media, Sera, Reagents)" report has been added to's offering.

Growth in the use of cell culture for biological research, vaccine production, the production of therapeutic proteins, and emerging regenerative medicine applications are driving the global cell culture market. As second-generation biologics such as monoclonal antibodies replace first-generation therapeutic proteins, there is also an increased demand for more advanced in vitro cell culture techniques with greater growing capacities.

This report is focused on cell culture used in the research and production of biopharmaceuticals, which includes stem cell therapeutics. Worldwide demand for cell culture products for use in the research, development, and production of biotherapeutic drugs is forecast to expand during the forecast period.

Market data provided in Global Cell Culture Markets include:

  • Global Cell Culture Market, 2012-2022 (mil US$)
  • Global Cell Culture Market by Segment, 2012-2022 (mil US$) (Media, Sera, Reagents, Total)
  • Global Cell Culture Market by Region/Country, 2017 (North America, Europe, UK/Ireland, Singapore/Malaysia, Japan, Korea, China, Rest of World)
  • Global Cell Culture Market by Region/Country, 2022 (North America, Europe, UK/Ireland, Singapore/Malaysia, Japan, Korea, China, Rest of World)
  • Cell Culture Market Share by Company, 2017

Media Market

The most significant recent trend in media is a shift from serum- and animal-component-containing media to serum-free and chemically defined media. Prior to 2000, cell culture media usually contained serum, which includes undefined growth promoting factors.

The report provides the following media market data:

  • Global Cell Culture Media Market, 2012 - 2022 (mil US$)
  • Global Cell Culture Media Market by Type, 2017 (%) (Serum-Free, Chemically Defined, Animal-Free)
  • Global Cell Culture Media Market by Type, 2022 (%) (Serum-Free, Chemically Defined, Animal-Free)

Sera Market

Serum has traditionally been used as the major supplement to cell culture media. Serum is a complex mix of albumins, growth factors, and growth inhibitors. Serum is one of the most important components of cell culture media and serves as a source for amino acids, proteins, vitamins (particularly fat-soluble vitamins such as A, D, E, and K), carbohydrates, lipids, hormones, growth factors, minerals, and trace elements. The most commonly used types are from fetal and calf bovine sources.

The report provides the following sera market data:

  • Global Cell Culture Sera Market, 2012-2022 (mil US$)
  • Global Cell Culture Sera by Type, 2017 (%) (Serum-Free, Chemically Defined, Animal-Free)
  • Global Cell Culture Sera by Type, 2022 (%) (Serum-Free, Chemically Defined, Animal-Free)

Reagent Market

The reagents segment of the cell culture market is driven by their increasing use in biotherapeutics research and production. Companies and research laboratories that work with cell culture want to grow cells cost efficiently and at the same levels as is possible with serum supplementation. Typically, this requires the addition of growth factors, lipids, substitutes for transferrin and albumin, compounds capable of detoxification, and specific attachment factors.

The report provides the following reagent market data:

  • Global Cell Culture Reagent Market, 2012 - 2022 (mil US$)
  • Global Cell Culture Reagent Market by Type, 2017 (%) (Cytokines & Growth Factors, Cell Dissociation Reagents, Buffers and Salt Solutions, Other Reagents)
  • Global Cell Culture Reagent Market by Type, 2022 (%) (Cytokines & Growth Factors, Cell Dissociation Reagents, Buffers and Salt Solutions, Other Reagents)


Biopharmaceuticals may increase life expectancy, decrease disability, and reduce the need for health services. The approved drugs include hormones, blood factors, thrombolytics, vaccines, interferons, mAbs, and therapeutic enzymes. In the pharmaceutical industry, cell culture is a major foundation of biopharmaceutical development, bioprocessing, and manufacturing. As growing cells for biopharmaceutical production is slow, expensive, and complicated, optimizing cell culture development is of paramount concern to companies developing biopharmaceuticals. Global Cell Culture Markets notes the top-selling biopharmaceuticals in 2015, 2016, and 2017; FDA-approved biopharmaceuticals in 2015, 2016, and 2017; and biosimilars approved for human use in the US.

Company Profiles

In a market characterized by a high level of concentration, cell culture product suppliers can increase market share and sustain margins by partnering with pharmaceutical companies, or by acquiring smaller producers or companies that manufacture specialty products.

The report profiles the major concerns in the cell culture market, including:

  • Analytical Biological Services Incorporated
  • Athena Enzyme Systems
  • Avantor Incorporated
  • BD Biosciences
  • Bio-Techne Corporation
  • BioreclamationIVT LLC
  • Cell Essentials Incorporated
  • CellGenix GmbH
  • Corning Life Sciences
  • GE Healthcare Life Sciences
  • Gemini Bio-Products
  • InVitria
  • Irvine Scientific Sales Company Incorporated
  • Kohjin Bio Company Limited
  • Lonza Group Limited
  • MilliporeSigma
  • MP Biomedicals LLC
  • Nissui Pharmaceutical Company Limited
  • PromoCell GmbH
  • Quality Biological Incorporated
  • SBH Sciences Incorporated
  • ScienCell Research Laboratories Incorporated
  • Selexis SA
  • Serana Europe GmbH
  • STEMCELL Technologies Incorporated
  • Takara Bio Incorporated
  • Thermo Fisher Scientific Incorporated
  • Wisent Incorporated

Cell culture products used in diagnostics are excluded from the scope of this study. The information for this report was gathered using both primary and secondary research, including comprehensive research of secondary sources such as company literature, databases, investment reports, and medical and business journals. Telephone interviews and email correspondence were the primary methods of gaining information.

Key Topics Covered:

1. Executive Summary

  • Biopharmaceuticals Primary Driver of Cell Culture Market
  • Cell Culture Reagents Will Offer the Best Opportunities Through 2022
  • The Asia/Pacific Region Is Expected to Post the Fastest Growth
  • Scope and Methodology

2. Biopharmaceuticals

  • Growth in Biopharmaceutical Production Boosts Demand for Cell Culture Products
  • Introduction to Biopharmaceuticals
  • Global Biopharmaceutical Market
  • Top Selling Biopharmaceuticals in 2015, 2016, and 2017
  • FDA-Approved Biopharmaceuticals
  • Biosimilars
  • Stem Cells in Research and as Biotherapeutics
  • Biopharmaceutical Production Considerations
  • Posttranslational Modifications
  • Upstream Processing vs Downstream Processing
  • Cell Culture Practices and Regulatory Guidelines
  • Validation of Facilities
  • Maintaining Sterilization Standards

3. Cell Culture Technologies

  • Introduction and Overview
  • Milestones in Cell Culture Development
  • Cells for Biopharmaceutical Production
  • Bacteria and Yeast Systems
  • Animal Cell Systems
  • Insect Cell Systems
  • Advantages/Disadvantages of Cell Culture Systems
  • Genetically Modified Cells for Biopharmaceutical Development
  • A Brief History of Biotechnology
  • Science of Genetic Manipulation
  • Dominant Cell Lines Utilized in Biopharmaceutical Production
  • Chinese Hamster Ovary (CHO)
  • SP2/0 and NS0
  • HEK293 and PER.C6
  • Cell Lines and Cell Banks
  • Fermentors and Bioreactors
  • Stirred-tank Reactors
  • Airlift Fermentors
  • Packed Bed Reactors
  • Hollow-fiber Reactors
  • Single-use/Disposable Systems
  • Perfusion Bioreactors
  • Fermentation Processes
  • Batch and Fed-Batch Fermentation
  • Suspended versus Adherent Cells
  • Microencapsulation
  • Advances in Cell Culture Technologies: 3D Cell Culture

4. Cell Culture Consumables

  • Cell Culture Environment
  • Functions and Components of Basal Media
  • pH and Osmotic Pressure
  • Energy Sources
  • Nutrients
  • Cell Culture Media
  • Lysogeny Broth (LB)
  • Classical Media
  • Serum-Free Media
  • Protein-Free Media
  • Chemically Defined Media
  • Specialty Media
  • Sera
  • Sources of Sera
  • Bovine Serum Safety Issues and Regulations
  • Shift to Serum-Free Media
  • Reagents
  • Major Types of Biological Reagents
  • Amino Acids
  • Growth Factors and Cytokines
  • Albumin
  • Transferrin
  • Thrombin
  • Growth Supplements
  • Protease Inhibitors
  • Attachment Factors
  • Shifting Toward Non-Animal Derived Reagents
  • Addressing Reagent Safety Issues

5. Cell Culture Market

  • Overview
  • Market Drivers
  • Current and Future Trends
  • Cell Culture-Based Vaccine Production
  • Impact of Biosimilars on the Cell Culture Market
  • Stem Cell Research Also Drives the Cell Culture Market
  • Cell Culture Market Forecast
  • Global Cell Culture Market Share by Region
  • Global Cell Culture Market Share by Region, 2017 and 2022
  • Asia Pacific Region Will Continue to Gain Market Share
  • China Expected to Become a Leading Biopharmaceuticals Market, Supporting Demand for Cell Culture
  • Cell Culture Product Market by Type
  • Media
  • Market Share by Media Type
  • Comparison of Serum versus Serum-Free Media
  • Liquid versus Powdered Media
  • Sera
  • Reagents
  • Reagent Types
  • Cytokines and Growth Factors
  • Cell Dissociation Reagents
  • Buffers and Salt Solutions
  • Other Reagents
  • Cell Culture Supplier Market Share
  • Market Leaders in Cell Culture, 2017
  • Acquisitions & Divestitures
  • Cooperative Agreements

6. Company Profiles

7. Appendix: Company Directory

For more information about this report visit

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                    Related Topics: Biotechnology


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